小型干法制粒機(jī)GZL100特點(diǎn)

1、整機(jī)懸臂式設(shè)計(jì)將加工區(qū)與動(dòng)力傳動(dòng)區(qū)*隔離且外形整潔，拆裝清洗簡(jiǎn)便，實(shí)現(xiàn)了從粉體到顆粒的潔凈密閉式生產(chǎn)。

2、操作屏采用304不銹鋼材質(zhì)制作，密封性好，可有效防塵、防濺，設(shè)計(jì)有脫氣壓力顯示及調(diào)節(jié)功能，另外還有鑰匙開(kāi)關(guān)、急停等功能，設(shè)備各運(yùn)行參數(shù)、緊急停機(jī)及切斷電源時(shí)均可通過(guò)觸摸屏即時(shí)操作。

3、所有與藥物接觸部分（工作腔）密閉獨(dú)立，密封均采用雙級(jí)以上組合密封，且密封符合FAD要求，旋轉(zhuǎn)軸采用漏軸式結(jié)構(gòu)，將傳動(dòng)區(qū)與制粒區(qū)嚴(yán)格分開(kāi)，避免了傳動(dòng)區(qū)內(nèi)潤(rùn)滑油泄露進(jìn)制粒區(qū)的情況。

4、制粒系統(tǒng)安裝有多處傳感器及儀表，用于實(shí)現(xiàn)系統(tǒng)的自動(dòng)化運(yùn)行，其安裝與設(shè)備內(nèi)部且采用不銹鋼材質(zhì)或其表面進(jìn)行防腐處理，符合GMP要求。

5、設(shè)備最小投料量100g，既可用于研發(fā)，亦可用于中試生產(chǎn)。

◆The cantilever design of the whole machine completely isolates the processing area from the power transmission area and has a neat appearance. It is easy to disassemble and clean, and realizes clean and closed production from powder to granules.

◆Operation screen is made of 304 stainless steel material, which has good sealing performance, can effectively prevent dust and splash, and is designed with degassing pressure display and adjustment functions. In addition, there are functions such as key switch, emergency stop, and various operating parameters of the equipment, emergency shutdown and When the power is cut off, it can be operated instantly through the touch screen.

◆All parts in contact with the medicine (working cavity) are airtight and independent. The seals are combined with two or more stages, and the seals meet the FAD requirements. The rotating shaft adopts a leaky shaft structure, which strictly separates the transmission area from the granulation area and avoids the transmission area. Lubricating oil leaked inside the grain area.

◆The granulation system is equipped with multiple sensors and instruments to realize the automatic operation of the system. The installation and the inside of the equipment are made of stainless steel or its surface for anti-corrosion treatment, which meets the requirements of GMP.

◆The minimum feeding amount of the equipment is 100g, which can be used for research and development as well as pilot production.

小型干法制粒機(jī)GZL100參數(shù)

設(shè)備依據(jù)干式制粒工藝的基本要求，將輕粉（游離水含量＜1.5%）經(jīng)過(guò)預(yù)壓縮→壓片成型→整粒成型三個(gè)步驟在不加粘合劑及水的條件下，制成不規(guī)則狀顆粒，完成從粉體至顆粒的物理變化過(guò)程。

1、 上料工序:物料被斷續(xù)放入垂直送料料倉(cāng)內(nèi)。
2、 垂直送料工序：干粉經(jīng)加料口進(jìn)入料斗，在中空型垂直鉸龍的作用下，將粉體推入水平式螺桿送料器，此過(guò)程中，部分氣體由鉸龍底部向上經(jīng)鉸龍空心部位被排出，使粉料能均勻的被送入水平螺桿送料口內(nèi)，送料量變頻可調(diào)，保證螺桿填充飽滿、均勻、不空、不堵，并使粉體的密度得到了初步的提高。
3、 水平送料工序：脫氣后的物料進(jìn)入水平送料器，通過(guò)螺桿的旋轉(zhuǎn)，使物料在前移過(guò)程中再次脫氣，并將提高密度的物料強(qiáng)制送入壓片系統(tǒng)，完成預(yù)壓工作。
4、 壓片工序：脫氣后的物料已經(jīng)具備了壓軋前的狀態(tài)，經(jīng)過(guò)預(yù)壓后進(jìn)入咬合區(qū)的物料與壓輥表面的磨擦力提高，減少了物料的磨擦，加大了咬入角，脫氣后的物料在壓軋成型過(guò)程中使設(shè)備運(yùn)行更加平穩(wěn)，成片強(qiáng)度均勻，質(zhì)量穩(wěn)定，成型后的壓片，經(jīng)下工序的破碎和整粒，粉化率明顯得到控制，很大限度地保證了產(chǎn)品的最終質(zhì)量。水冷式壓輥，接頭外置，使工作區(qū)無(wú)漏水污染的可能，并便于清理。
5、 整粒工序：在整粒系統(tǒng)，經(jīng)破碎后的料片進(jìn)入整粒機(jī)，在整粒刀的擠壓下，小顆粒很容易通過(guò)整粒機(jī)的孔板，不再發(fā)生破損，而大顆粒繼續(xù)在整粒機(jī)中被擠壓破碎為小顆粒，在此完成所需顆粒目數(shù)的圓整工作。整粒刀為連續(xù)轉(zhuǎn)動(dòng)，效率高。至此完成由干粉至顆粒的全部生產(chǎn)過(guò)程。